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Salvia divinorum is a perennial herb in the mint family native
to certain areas of the Sierra Mazateca region of Oaxaca,
Mexico. The plant, which can grow to over three feet in height,
has large green leaves, hollow square stems and white flowers
with purple calyces, can also be grown successfully outside
of this region . Salvia divinorum has been used by the Mazatec
Indians for its ritual divination and healing. The active
constituent of Salvia divinorum has been identified as salvinorin
A. Currently, neither Salvia divinorum nor any of its constituents,
including salvinorin A, are controlled under the federal Controlled
Substances Act (CSA). However, the abuse of Salvia Divinorum
is gaining popularity in the United States, particulary by
adolescents and young adults.
Street Names:
Maria Pastora, Sage of the Seers, Diviner’s Sage, Salvia,
Sally-D, Magic Mint
Short Term Effects:
A limited number of studies have reported the effects of using
either plant material or salvinorin A. Psychic effects include
perceptions of bright lights, vivid colors and shapes, as
well as body movements and body or object distortions. Other
effects include dysphoria, uncontrolled laughter, a sense
of loss of body, overlapping realities, and hallucinations
(seeing objects that are not present). Adverse physical effects
may include incoordination, dizziness, and slurred speech.
Scientific studies show that salvinorin A is a potent and
selective kappa opioid receptor agonist. Other drugs that
act at the kappa opioid receptor also produce hallucinogenic
effects and dysphoria similar to that produced by salvinorin
A. Salvinorin A does not activate the serotonin 2A receptor,
which mediates the effects of other schedule I hallucinogens.
Due to the hallucinogenic effects there is a substantial risk
of injury or death as a result of impaired judgment due to
disruptions of sensory and cognitive functions.
Information contained above is courtesy of
U.S. Drug Enforcement Administration for more information
please visit:
http://www.usdoj.gov/dea/concern/salvia_divinorum.html
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